The 3rd International Danube Symposium
Recently introduced total-body PET systems offer a paradigm shift in medical sciences by providing a comprehensive assessment of the entire patient, considering their biological and clinical state, rather than just isolated diseases or organs. This new and innovative technology enables researchers and healthcare providers to capture total body tracer kinetics, from which quantitative whole body functional parametric images can be obtained. These data provide a means to assess interorgan communication and track the transition from health to disease. As a result, this technology holds the potential to yield a more complete understanding of the subject‘s overall health in real time and their progression over time with clinical interventions. “Enabling Whole-Person Research: The Transformative Impact of Total-Body PET, Complexity Science, and Network Medicine“ is organized as an international, cross- discipline symposium aiming to explore the role of total-body Positron Emission Tomography (PET) within a symbiotic partnership with network medicine and complexity sciences. This collaboration seeks to advance medical and clinical sciences towards holistic health research. To fully unlock the potential of total-body PET imaging, appropriate research questions along with corresponding paradigms and protocols must be developed. Advanced computational tools and novel workflows are essential to process the vast amounts of data generated by these systems, addressing clinical research questions and aiding in clinical decision-making. This symposium will convene experts from nuclear medicine, molecular biology, physiology, network medicine, and data sciences. Their collective goal is to assess the current state-of-the-art in their respective domains and to formulate paradigms and protocols for a better comprehension of whole-person health and disease.
Marcus Hacker
Medical University of Vienna
Thomas Beyer
Medical University of Vienna
The symposium will showcase invited presentations by renowned experts in various complementary fields. Moderated debates will be organized along organ axes and physiological interventions. This forward-looking event aims to foster the creation of a cross-specialty community, bringing together experts from diverse disciplines to drive forward the research on whole-person health. This initiative will also complement other meetings that might be more technically or clinically focused. We invite you to join us and become an integral part of this innovative and ambitious community, united in the common goal of advancing the realm of medical and clinical research. Marcus Hacker and Thomas Beyer Scientific Organizational Team
Program
Thursday, 21st September 2023
Welcome and Motivation
Scientific Organizational Team
Basic I: How to endotype and redefine diseases and validate this by clinical trials
Harald Schmidt Moderator: Marcus Hacker
Basic II: Molecular imaging and TB-PET
Simon Cherry
Moderator: Thomas Beyer
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The organization of biology
Moderator: Thomas Beyer
Unlocking the secrets of biology through art, imaging and data science
Julia Guthrie Pazmandi
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Navigating big and bigger complexity to uncover the secrets of health data
Jean-Luc Balligand
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The network effect: examining inflammation in the body
Moderator: Jean-Luc Balligand
Stress and the cardiovascular system: navigating the intersection
Ahmed Tawakol
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Immune interactions in chronic inflammation: old friends and new foes
Christoph Binder
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Inflammation interactions: understanding cross-talk in the body
Thorsten Derlin
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The network effect: examining inflammation in the body II
Moderator: Ed Silverman
Defending the organs: understanding organ-specific immune responses
Christoph Bock
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Novel translational applications in immunology and oncology using total body PET
Christian la Fougère
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Case story: proliferation, metabolic networks and stress intervention
Moderator: Christoph Binder
Stress and lung cancer
Marcus Hacker
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Lung cancer induced cachexia
Armin Frille
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Friday, 22nd September 2023